I’m most successful with managing the projects and daily requests of my many internal clients when I reply to each message with as complete of a response as possible. Once that message has moved down the list it is out of mind -- leaving tasks incomplete. So, I review the proposed content or provide analytics or whatever is requested as soon as I read the message. That doesn’t mean that I’m constantly interrupted -- but when it is time for me to manage my incoming messages -- I handle each request to my capacity. Then add any remaining elements to my To Do list for the next day.